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Drug Delivery System:

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. Sustained Release(SR) and Controlled Release (CR) formulations: Introduction & basic concepts, advantages/ disadvantages, factors influencing, Physicochemical & biological approaches for SR/CR formulation, Mechanism of Drug Delivery from SR/CR formulation. Polymers: introduction, definition, classification, properties and application Dosage Forms for Personalized Medicine: Introduction, Definition, Pharmacogenetics, Categories of Patients for Personalized Medicines: Customized drug delivery systems, Bioelectronic Medicines, 3D printing of pharmaceuticals, Telepharmacy. 10 Hrs 2 Rate Controlled Drug Delivery Systems: Principles & Fundamentals, Types, Activation; Modulated Drug Delivery Systems;Mechanically activated, pH activated, Enzyme activated, and Osmotic activated Drug Delivery Systems Feedback regulated Drug Delivery Systems; Principles & Fundamentals. 10 Hrs 3 Gastro-Retentive Drug Delivery Systems: Principle, concepts advantages and disadvantages, Modulation of GI transit time approaches to extend GI transit. Buccal Drug Delivery Systems: Principle of muco adhesion, advantages and disadvantages, Mechanism of drug permeation, Methods of formulation and its evaluations. 4 Occular Drug Delivery Systems: Barriers of drug permeation, Methods to overcome barriers. 10 Hrs 06 Hrs 39 5 Transdermal Drug Delivery Systems: Structure of skin and barriers, Penetration enhancers, Transdermal Drug Delivery Systems, Formulation and evaluation. 6 Protein and Peptide Delivery: Barriers for protein delivery. Formulation and Evaluation of delivery systems of proteins and other macromolecules. 10 Hrs 08 Hrs 7 Vaccine delivery systems: Vaccines, uptake of antigens, single shot vaccines, mucosal and transdermal delivery of vaccines.

Target Drug Delivery

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1. Targeted Drug Delivery Systems: Concepts, Events and biological process involved in drug targeting. Tumor targeting and Brain specific delivery. 2 Targeting Methods: introduction preparation and evaluation. Nano Particles & Liposomes: Types, preparation and evaluation. 12 Hrs 12 Hrs 3 Micro Capsules / Micro Spheres: Types, preparation and evaluation , Monoclonal Antibodies ; preparation and application, preparation and application of Niosomes, Aquasomes, Phytosomes, Electrosomes. 4 Pulmonary Drug Delivery Systems : Aerosols, propellents, ContainersTypes, preparation and evaluation, Intra Nasal Route Delivery systems; Types, preparation and evaluation. 5 Nucleic acid based therapeutic delivery system : Gene therapy, introduction (ex-vivo & in-vivo gene therapy). Potential target diseases for gene therapy (inherited disorder and cancer). Gene expression systems (viral and nonviral gene transfer). Liposomal gene delivery systems. Biodistribution and Pharmacokinetics. knowledge of therapeutic antisense molecules and aptamers as drugs of future.

Novel Drug Delivery System:

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Concept & Models for NDDS: Classification of rate controlled drug delivery systems (DDS), rate programmed release, activation modulated & feedback regulated DDS, effect of system parameters in controlled drug delivery, computation of desired release rate and dose for controlled release DDS, pharmacokinetic design for DDS – intermittent, zero order & first order release. Carriers for Drug Delivery: Polymers / co-polymersintroduction, classification, characterization, polymerization techniques, application in CDDS / NDDS, biodegradable & natural polymers. 12 Hrs 2 Study of Various DDS: Concepts, design, formulation & evaluation of controlled release oral DDS, Mucoadhesive DDS (buccal, nasal, pulmonary) Pulsatile, colon specific, liquid sustained release systems, Ocular delivery systems 12 Hrs 3 Transdermal Drug Delivery Systems: Theory, design, formulation & evaluation including iontophoresis and other latest developments in skin delivery systems. 08 Hrs 4 Sub Micron Cosmeceuticals: Biology, formulation science and evaluation of various cosmetics for skin, hair, nail, eye etc and it’s regulatory aspects. 04 Hrs 59 5 Targeted Drug Delivery Systems: Importance, concept, biological process and events involved in drug targeting, design, formulation & evaluation, methods in drug targeting – nanoparticles, liposomes, niosomes, pharmacosomes, resealed erythrocytes, microspheres, magnetic microspheres. Specialized pharmaceutical emulsions – multiple emulsions, micro-emulsions. 12 Hrs 6 Protein / Peptide Drug Delivery Systems: Concepts, delivery techniques, formulation, stability testing, causes of protein destabilization, stabilization methods. 7 Biotechnology in Drug Delivery Systems: Brief review of major areas-recombinant DNA technology, monoclonal antibodies, gene therapy. 06 Hrs 8 New trends for Personalized Medicine: Introduction, Definition, Pharmacogenetics, Categories of Patients for Personalized Medicines: Customized drug delivery systems, Bioelectronic Medicines, 3D printing of pharmaceuticals, Telepharmacy.

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Certainly! Here's an example table of contents for a book on Drug Delivery:

Table of Contents

Preface

  • About This Book

  • Acknowledgments

  • How to Use This Book

Chapter 1: Introduction to Drug Delivery

  • 1.1 Overview of Drug Delivery

  • 1.2 Historical Development

  • 1.3 Significance and Challenges

  • 1.4 Scope and Objectives of the Book

Chapter 2: Drug Delivery Systems and Technologies

  • 2.1 Classification of Drug Delivery Systems

  • 2.2 Oral Drug Delivery

  • 2.3 Injectable and Parenteral Delivery

  • 2.4 Topical and Transdermal Delivery

Chapter 3: Drug Release Mechanisms

  • 3.1 Principles of Drug Release

  • 3.2 Diffusion-Controlled Release

  • 3.3 Erosion-Controlled Release

  • 3.4 Stimuli-Responsive Release

Chapter 4: Formulation Development

  • 4.1 Drug Formulation Basics

  • 4.2 Excipients and Additives

  • 4.3 Formulation Optimization

  • 4.4 Challenges in Formulation Development

Chapter 5: Controlled and Targeted Drug Delivery

  • 5.1 Controlled Release Systems

  • 5.2 Targeted Drug Delivery Approaches

  • 5.3 Nanoparticle-Based Delivery

  • 5.4 Personalized Drug Delivery

Chapter 6: Drug Delivery Routes

  • 6.1 Oral Drug Delivery

  • 6.2 Injectable and Parenteral Delivery

  • 6.3 Topical and Transdermal Delivery

  • 6.4 Pulmonary and Inhalation Delivery

Chapter 7: Biopharmaceutical Considerations

  • 7.1 Drug Absorption and Bioavailability

  • 7.2 Drug Distribution and Metabolism

  • 7.3 Pharmacokinetics and Pharmacodynamics

  • 7.4 Drug-Drug Interactions

Chapter 8: Drug Delivery in Special Populations

  • 8.1 Pediatric Drug Delivery

  • 8.2 Geriatric Drug Delivery

  • 8.3 Drug Delivery in Pregnancy

  • 8.4 Challenges in Special Population Delivery

Chapter 9: Regulatory and Quality Considerations

  • 9.1 Regulatory Framework for Drug Delivery Systems

  • 9.2 Quality Control and Assurance

  • 9.3 Intellectual Property and Patents

  • 9.4 Responsible Drug Delivery Practices

Chapter 10: Challenges and Future Directions

  • 10.1 Current Challenges in Drug Delivery

  • 10.2 Emerging Technologies and Innovations

  • 10.3 Smart Drug Delivery Systems

  • 10.4 The Future of Drug Delivery

Appendix A: Glossary

  • Key Terms and Definitions

Appendix B: Drug Delivery Resources

  • Recommended Books, Journals, and Organizations

Index

This table of contents provides a structured outline for a comprehensive book on Drug Delivery. You can customize it further to match the specific focus and goals of your book.

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